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Locals prefer to eat at sizzling Spanish restaurant Las Tapas (Schneider-Wibbel-Gasse 4), cosy Italian trattoria La Castagnas (Rossstrasse 9) or Japanese eatery Monkey? Düsseldorf also has a fine selection of Michelin-star restaurants, including starkly traditional Victorian (Königstrasse 3a) and the wonderful Nagaya (Klosterstrasse 42), which blends European and Japanese cuisine and offers a locally famous sushi buffet.
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Budget travellers will find stylish accommodation at B&B Hotel (Kettwiger Strasse 6).
The Altstadt area is home to a range of pint-sized boutiques selling everything from kitsch souvenirs to designer bargains, but Düsseldorf's retail scene is largely dominated by modern malls and department stores.
Designer label devotees should also check out upmarket mall Schadow Arkaden (Schadowstrasse 11).
Weekend antique fairs and flea markets run throughout the year, with the majority taking place in the area around Schützenplatz.
The authors identified 4 factors that were able to differentiate patients into 3 risk categories with expectant median survivals ranging from 11 months to 93 months.